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mcRigor-package mcRigor
mcRigor: a statistical tool to enhance the rigor of metacell partitioning
mcRigor_DETECT()
Main functionality 1: To detect dubious metacells for a given metacell partition
mcRigor_OPTIMIZE()
Main functionality 2: To select the optimal hyperparameter for metacell partitioning
mcRigor_buildmc()
To build an metacell object from the given metacell partitioning
mcRigor_covariate()
To assist metacell object building in determining the metacell covariates (metadata)
mcRigor_projection()
To visualize a given metacell partitioning by projecting metacells onto the single cell embedding space.
mcRigor_purity()
To assist metacell object building in compute the purity of metacells with respect to each covariate
mcRigor_threshold()
A building block of the main functions. To derive the thresholds for detecting dubious metacells based on the output permutation results (TabMC)
mcRigor_tradeoff()
A building block of the main functions. To evaluate each metacell partition and optimize metacell partitioning based on the output permutation results (TabMC) and thresholds (threshold)